TDMR Europe Chair discusses TDR’s contribution to type 2 diabetes remission on EAWAZ TV

Posted On: 21st April 2023

TDMR Europe Chair, Professor Anthony Leeds is featured in the Health Chats programme of EAWAZ TV, discussing the role of weight loss with Total Diet Replacement (TDR) in type 2 diabetes (T2DM) remission for adults with obesity.

In the video interview, Dr Leeds discusses the ‘DiRECT’ diabetes remission trial with Professor Mike Lean from Glasgow University. Undertaken in a primary care setting, DiRECT saw almost half of those who went on a low-calorie diet with TDR achieve remission of their T2DM after one year. A quarter of participants achieved a 15kg or more weight loss, and of these, 86% put their T2DM into remission.

The ‘DiRECT’ trial was a study largely on white British participants and the speakers emphasised the need for similar studies in other population groups. In this context, Professor Lean touched on the STANDBY trial, another study run by the University of Glasgow that used TDR to help people of South Asian ethnicity with obesity and T2DM lose weight and improve their T2DM. In this trial, UK-based South Asians were recruited through primary care and social media, and randomised to commence a TDR programme. According to the results of the study, 35% of the participants lost over 10% bodyweight and 43% achieved T2DM remission.

The DiRECT and STANDBY studies are part of the increasing evidence showing the potential of TDRs to address obesity and improve related diseases in Europe. Decision makers need to prioritise tackling obesity and look into all available options, including TDRs. Businesses in the sector meanwhile need to work together to help policy makers develop a greater understanding of these products.

TDMR Europe works to help stakeholders develop a better understanding of formula diet foods and aims to increase awareness of the scientific evidence showing the effectiveness of these products in tackling obesity and improving related comorbidities. Find out more here.

More information on the use of TDR for weight loss and diabetes remission and prevention is available here.

You can find more information on diabetes remission and maintenance after weight loss with TDR here.

Find out more about the DiRECT trial here.